New findings on botox therapy

Author:
Dr Hans Halten
Datum:
July 24, 2025

An American study on the effectiveness of botulinum toxin (BoNT) has

daily practice found new relevant connections:

  1. It is not surprising that the location of the injection is important for the optimal effectiveness of BoNT. What is new, however, is the finding that the effectiveness is particularly good when the injection is carried out in the area of the motor end plate of the muscle
  2. The uptake of BotN into the muscle is reduced by previous or subsequent cooling.
  3. On the other hand, increased activity of the treated muscles for about 5 to 10 minutes after the treatment is helpful.
  4. A zinc deficiency can reduce the effectiveness of BoNT or shorten the duration of the effect.

Summary:

To optimize the effect, BoNT should be injected into the area of the motor end plate of the muscle. Cold applications before or after treatment should be avoided. Immediately after the injection, the treated area should be actively moved for approximately 5 to 10 minutes. This optimizes the absorption of BotN into the muscle. 3 to 4 days before treatment, taking zinc capsules can improve the effectiveness and duration of the effect.

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